Every person seeks satisfying answers to existential questions related to the God’s existence, origins, personal identity, the problem of evil and suffering, purpose, morality, and the afterlife (to mention a few). The Holy Scriptures provide adequate, coherent, consistent, and satisfying answers to these existential questions. Furthermore, the Holy Scriptures consisting of the Old and New Testaments form the framework for the Christian Worldview. More specifically, in the NT letter to the Romans, the apostle Paul reflects several fundamental aspects of the biblical worldview. He addressed this letter specifically to the Christians in Rome. At the time the church in Rome consisted of Jewish and Gentile believers. The Roman Christians came from divergent backgrounds and cultures. First-century Rome was a major cosmopolitan city that provided an arena for the expression of multiple worldviews. Paul wrote to the Christians in Rome in order to address specific concerns and challenges they were facing. Even though Romans was an occasional letter (i.e., not a systematic theology), Paul presents the Gospel of Jesus Christ in a systematic fashion. The Gospel is the overarching theme of Romans as Paul spells out in his programmatic statement in 1:16–17. As the systematic presentation of the Gospel of Jesus Christ, Romans is foundational to the Christian Worldview. Recognizing that Romans does not contain all the essential truths that are relevant to a worldview, the apostle Paul expresses truths that are foundational to the Christian worldview. The foundational aspects of the Christian worldview that are expressed in Romans include the following: God is Creator and Judge; sin has negatively affected creation in general and humanity in particular; God provided the solution to the problem of evil; God has established an ethical and moral standard; and God’s purposes in Christ certainly will be realized. Paul’s biblical worldview provides consistent answers to existential questions posed in every age of humanity. Furthermore, Paul’s biblical worldview informs a biblical theology of humanity.