Many interpreters view Lady Wisdom in Proverbs as the personification of Yahweh’s wisdom. Even more, her lengthy speech in Proverbs 8 affords her a quasi-divine status. This text in turn became the locus of debate over Christ’s nature among the church fathers, with many early theologians, Arians and orthodox alike, resorting to the text to support their respective sides. In this paper I trace this debate among the church fathers, highlighting key proponents championing the various positions. I then argue exegetically from Proverbs that the Nicene fathers were not imposing a theological category on Proverbs but following exegetical warrant for their understanding. I argue that Lady Wisdom prefigures the Messianic God-Man in three key areas: (1) Wisdom speaks and acts as Yahweh and yet is distinct from Yahweh; (2) Wisdom takes on Messianic roles as a literary prophet, priest, and king; and (3) Wisdom is depicted with terminology most consistent with the biblical doctrine of eternal generation. I conclude by drawing out implications for grounding Christology in a portion of Scripture often neglected in these discussions, the wisdom books.